CombiPatch Warnings and Precautions

To help ensure safe treatment with CombiPatch, warnings and precautions for the medication should be discussed with your healthcare provider beforehand. Prior to starting treatment, you should tell your healthcare provider if you have asthma, high blood pressure, high cholesterol, or other existing medical conditions. You should not use CombiPatch if you have undiagnosed abnormal genital bleeding, liver disease, or a history of breast cancer.

CombiPatch Hormone Information

CombiPatch: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using CombiPatch^® (estradiol/norethindrone patch) if you have:

Had a heart attack, blood clot, or stroke
Heart disease or heart problems of any kind
Cancer (or if you have had cancer in the past)
High blood pressure, high cholesterol, or high triglycerides
Unexplained vaginal bleeding
Gallbladder disease
Diabetes
Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
Asthma
Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
Systemic lupus erythematosus (SLE, or lupus)
Migraine headaches
Hepatic hemangioma (a kind of liver tumor)
Porphyria (a condition involving problems with certain enzymes in the body)
Seizures or epilepsy
Kidney disease, including kidney failure (renal failure)
An underactive thyroid (hypothyroidism)
Endometriosis
Any allergies, including allergies to drugs, foods, preservatives, or dyes.

Also, let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant
Are breastfeeding
Have an upcoming surgery
Smoke cigarettes.

Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(CombiPatch Warnings and Precautions Continued: Page 2)