CombiPatch Warnings and Precautions
To help ensure safe treatment with CombiPatch, warnings and precautions for the medication should be discussed with your healthcare provider beforehand. Prior to starting treatment, you should tell your healthcare provider if you have asthma, high blood pressure, high cholesterol, or other existing medical conditions. You should not use CombiPatch if you have undiagnosed abnormal genital bleeding, liver disease, or a history of breast cancer.
You should talk with your healthcare provider prior to using CombiPatch® (estradiol/norethindrone patch) if you have:
- Had a heart attack, blood clot, or stroke
- Heart disease or heart problems of any kind
- Cancer (or if you have had cancer in the past)
- High blood pressure, high cholesterol, or high triglycerides
- Unexplained vaginal bleeding
- Gallbladder disease
- Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
- Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
- Systemic lupus erythematosus (SLE, or lupus)
- Migraine headaches
- Hepatic hemangioma (a kind of liver tumor)
- Porphyria (a condition involving problems with certain enzymes in the body)
- Seizures or epilepsy
- Kidney disease, including kidney failure (renal failure)
- An underactive thyroid (hypothyroidism)
- Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Have an upcoming surgery
- Smoke cigarettes.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.