Climara Warnings and Precautions

Before starting hormone replacement therapy with Climara, warnings and precautions for the drug should be discussed with your healthcare provider. It is important to know that Climara may increase the risk of dementia, breast cancer, and gallbladder disease. It can also worsen certain medical conditions, so it is important to tell your healthcare provider about any existing conditions you have, including asthma, migraines, or diabetes.

Climara Patch Information

Climara: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Climara^® (estradiol patch) if you have:

Heart disease or heart problems of any kind
Cancer (or if you have had cancer in the past)
Had a heart attack or stroke
Had a blood clot
Gallbladder disease
High cholesterol or high triglycerides
High blood pressure (hypertension)
Diabetes
Had yellowing of the whites of the eyes or skin (jaundice) during a prior pregnancy or estrogen use
Systemic lupus erythematosus (SLE or lupus)
Migraines
Hepatic hemangioma (a kind of liver tumor)
Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
Asthma
Porphyria (a condition involving problems with certain enzymes in the body)
Seizures or epilepsy
Kidney disease, including kidney failure (renal failure)
An underactive thyroid (hypothyroidism)
Endometriosis
Unexplained vaginal bleeding
Any allergies, including allergies to drugs, foods, preservatives, or dyes.

Also, let your healthcare provider know if you:

Have an upcoming surgery
Smoke cigarettes
Are pregnant or thinking of becoming pregnant
Are breastfeeding.

Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Climara Warnings and Precautions Continued: Page 2)