Climara Drug Interactions

If grapefruit juice, rifamycin antibiotics, or certain seizure medications are combined with Climara, drug interactions may occur. This can affect the level of Climara in your blood, which could decrease its effectiveness or increase your risk for developing side effects. Other medications that may lead to Climara interactions include St. John's wort, various antifungals or antibiotics, cyclosporine, and thyroid replacement medicines.

An Introduction to Climara Drug Interactions

Climara® (estradiol patch) has the potential to interact with numerous other medications. Some of the medicines that may lead to Climara interactions include:
 
  • Barbiturates, including (but not limited to):

 

    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)

 

  • Certain seizure medications, such as:

 

 

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
  • St. John's wort (Hypericum perforatum), an herbal supplement
  • Thyroid replacement medications, including:

 

 

  • Various antifungal medications or antibiotics, such as:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®).

 

Good Food, Good Bones

Climara Patch Information

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