Products That Interfere With Climara

Climara Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Climara is combined with any of the drugs listed above.
 
Barbiturate Medications
Barbiturates may cause your body to metabolize the hormones in Climara too rapidly, leading to low levels of Climara in the body. This can make Climara less effective, but it is not a serious drug interaction.
 
Certain Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in Climara too quickly, leading to low levels of Climara in the body. Although this can make Climara less effective, it is not a dangerous drug interaction.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Climara may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to one of the many Climara alternatives.
 
Grapefruit Juice
Grapefruit juice may decrease the ability of your liver to metabolize Climara, leading to high levels of Climara in the body. This may increase the risk of Climara side effects.
 
Protease Inhibitors
Protease inhibitors may decrease the ability of your liver to metabolize Climara, leading to high levels of Climara in the body. This may increase the risk of Climara side effects. Check with your healthcare provider before combining Climara with a protease inhibitor.
 
Rifamycin Antibiotics
Rifamycin antibiotics may cause your body to metabolize the hormones in Climara too quickly, leading to low levels of Climara in the body. Although this can make Climara less effective, it is not a dangerous drug interaction.
Men and Osteoporosis

Climara Patch Information

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