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Climara Pro
Climara Pro is licensed for treating certain menopausal symptoms, such as hot flashes and night sweats. This prescription medication is also approved to prevent osteoporosis in postmenopausal women. It comes in the form of a patch that is applied to the skin once a week. Potential side effects can include breast pain, skin reactions, and unexplained vaginal bleeding.
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Climara Pro® (estradiol/levonorgestrel patch) is a prescription hormone replacement medication that contains estrogen. It comes as a patch that is applied to the skin once a week. The drug is approved for the following uses:
- Treating hot flashes or night sweats due to menopause
- Preventing osteoporosis in postmenopausal women.
For all uses, Climara Pro is only appropriate for women who still have a uterus (who have not had a hysterectomy).
(Click Climara Pro Uses for more information, including possible off-label uses.)
Climara Pro is made by Bayer HealthCare Pharmaceuticals, Inc.
How Does Climara Pro Work?
This prescription drug contains estradiol, one of several different estrogen hormones. Estradiol is the predominant estrogen in premenopausal women, and the estradiol in Climara Pro is identical to the hormone naturally made by the body.
Climara Pro helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce. Because estrogen helps to keep bones strong, the decrease that occurs during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, the medication can help prevent these menopause-related bone changes.
Levonorgestrel, a progestin, is added to Climara Pro because women who take estrogens without a progestin have an increased risk of cancer of the lining of the uterus. Levonorgestrel decreases this risk. Of course, this applies only to women who still have a uterus (who have not had a hysterectomy). For women without a uterus, the levonorgestrel component is usually considered unnecessary.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



