Clinical Effects

Brisdelle has been studied in clinical trials that included women who were having at least 7 to 8 moderate-to-severe hot flashes a day for at least 30 days. In these studies, Brisdelle reduced hot flashes more than a placebo (a "sugar pill" with no active ingredients). For example, in one study, women taking Brisdelle had about 5.6 fewer hot flashes each day after 24 weeks of treatment. In comparison, women given a placebo had about 3.9 fewer hot flashes a day.

When and How to Take It

Some general considerations to keep in mind during treatment with Brisdelle include the following:
  • Brisdelle comes in the form of a capsule. It is usually taken by mouth once a day, at bedtime.
  • This medication can be taken with or without food. Try taking it with food if it upsets your stomach.
  • You should take your dose at the same time each day to keep an even level of the drug in your bloodstream.
  • If Brisdelle does not seem to be reducing the number or severity of your hot flashes, let your healthcare provider know. It may not be the right medicine for you.  
  • Brisdelle can cause drowsiness. Do not drive, operate heavy machinery, or engage in any activity that requires mental alertness until you know how the medication affects you.
  • For the medication to work properly, it must be taken as prescribed. This medication will not work if you stop taking it.  

Dosing Information

There is only one standard recommended dose of Brisdelle, regardless of your age or weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Brisdelle Dosage for more information.)
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Brisdelle Medication Information

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