Brisdelle and Breastfeeding

The active ingredient in Brisdelle (paroxetine mesylate capsules) does pass through breast milk. Although only a small amount of the medication passes through, it may cause problems in a breastfed infant. The manufacturer of the medication recommends that breastfeeding women either stop taking Brisdelle or stop breastfeeding due to the potential risks to the infant.


Can Breastfeeding Women Take Brisdelle?

Brisdelle™ (paroxetine mesylate capsules) is a prescription medicine that belongs to a group of medications known as selective serotonin reuptake inhibitors (SSRIs for short). It is a non-hormonal treatment for hot flashes due to menopause. Brisdelle is known to pass through breast milk. Therefore, if you are nursing a child, talk with your healthcare provider before taking this medication.

More Information on Brisdelle and Breastfeeding

Studies have shown that the active ingredient in Brisdelle, paroxetine, passes through breast milk in small amounts. In most cases, there have been no notable side effects in breastfed infants whose mothers took paroxetine.
However, there have been cases where side effects, such as irritability, constipation, sedation, and difficulty feeding, have been reported. Most of these side effects occurred when the mothers also took paroxetine during pregnancy, making it difficult to determine whether the side effects were due to paroxetine during breastfeeding or during pregnancy.  
Even though the amount of paroxetine found in breast milk is very small, the possibility exists that it is large enough to cause problems in a nursing infant later in life. At this time, the potential for paroxetine to cause long-term effects in a nursing infant has not been studied. For this reason, the American Academy of Pediatrics calls paroxetine a medicine for which the effects on a nursing infant are unknown, but potentially concerning.
The recommendations for paroxetine use during breastfeeding are conflicting. The manufacturer of Brisdelle recommends that breastfeeding women either stop taking Brisdelle, or stop breastfeeding, due to the potential risks in a nursing child. Likewise, some experts recommend that women who are taking paroxetine stop breastfeeding or breastfeed less often.
However, since the amount of paroxetine that passes through breast milk is small, other experts consider the medicine compatible with breastfeeding. Avoiding breastfeeding four to six hours after taking a dose, when blood levels of paroxetine are at their highest, may help limit the amount of drug passed to a nursing infant.
If your healthcare provider recommends breastfeeding during Brisdelle treatment, be sure to watch for any potential Brisdelle side effects in your child.
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Brisdelle Medication Information

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