Certain Antidepressants
Research suggests that
black cohosh may affect the way your body handles certain
antidepressants, possibly increasing the level of the antidepressant in your blood (and increasing your risk of side effects). Until more information is available, it may be a good idea to avoid combining black cohosh with these antidepressants.
Cisplatin (Platinol)
Animal studies suggest that black cohosh can make cisplatin less effective for treating
breast cancer. Check with your healthcare provider before taking black cohosh if you are undergoing chemotherapy with cisplatin.
Codeine
It is thought that black cohosh may slow the breakdown of codeine in your body, perhaps increasing your risk of codeine side effects. It may be a good idea to avoid taking codeine and black cohosh together.
Flecainide (Tambocor)
Combining flecainide with black cohosh may slow the breakdown of flecainide in your body, perhaps increasing your risk of side effects of flecainide (which can be dangerous). Do not take flecainide and black cohosh together without first talking to your healthcare provider.
Haloperidol (Haldol)
It is thought that black cohosh may slow the breakdown of
haloperidol in your body, perhaps increasing your risk of
side effects of haloperidol. Check with your healthcare provider before taking haloperidol with black cohosh.
Metoprolol (Lopressor, Toprol XL)
Black cohosh may affect the way your body handles
metoprolol, perhaps increasing the level of metoprolol in your blood (and increasing your risks of side effects). It may be a good idea to avoid taking metoprolol and black cohosh together.
Ondansetron (Zofran)
It is thought that black cohosh may slow the breakdown of
ondansetron in your body, perhaps increasing your risk of
side effects of ondansetron. It may be a good idea to avoid taking ondansetron and black cohosh together.
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