Angeliq is used for treating moderate to severe hot flashes, night sweats, and vaginal symptoms due to menopause. This prescription medication contains both an estrogen and a progesterone hormone, and is only approved for women who still have a uterus. For women who have had a hysterectomy, the progesterone component is usually considered unnecessary. Occasionally, healthcare providers may recommend off-label Angeliq uses, such as for the prevention of osteoporosis in postmenopausal women.
What Is Angeliq Used For?
Angeliq® (drospirenone/estradiol) is a prescription hormone medication that contains estrogen and progestin hormones. It is the only hormone replacement medication that contains drospirenone ("drsp").
Approved Angeliq uses include:
- Treating moderate to severe night sweats and hot flashes due to menopause
- Treating moderate to severe itching, burning, or dryness in or around the vagina due to menopause.
For these uses, Angeliq is only approved for women who still have a uterus (who have not had a hysterectomy). If you have had a hysterectomy, the drospirenone component is usually considered unnecessary.
Menopause is a normal change in a woman's life when she stops having her period. That's why some people call menopause "the change of life." A woman has reached menopause when she has not had a period for an entire year and there are no other causes for this change. Menopause symptoms include:
- Vaginal changes, such as dryness or irritation
- Changes in your period, including abnormal bleeding or "spotting"
- Hot flashes (sometimes known as hot flushes)
- Mood changes
- Urinary problems
- Problems with concentration or memory
- Night sweats and sleeping problems (including insomnia)
- Thinning and weakening of your bones
- Less interest in sex and changes in sexual response
- Weight gain or an increase in body fat around your waist
- Hair thinning or loss.
For some women, these symptoms are quite severe, and some form of menopause relief may be necessary. This may include medications, natural menopause relief remedies, or non-medical ways to deal with the symptoms.
Angeliq contains an estrogen (estradiol) and a progestin hormone (drospirenone). It helps to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce.
Drospirenone ("drsp") is added to Angeliq because giving estrogens without a progestin to postmenopausal women can increase the risk of cancer of the lining of the uterus. Drospirenone (which is a progestin) decreases this risk. Of course, this applies only to women who still have a uterus (who have not had a hysterectomy). For women without a uterus, the drospirenone component is usually considered unnecessary.
Angeliq is different from traditional hormone replacement medications in one important way. The progestin that it contains (drospirenone) is more similar to natural progesterone, compared to other synthetic progestins. Drospirenone is closely related to spironolactone, a medication used as a diuretic ("water pill"). Like spironolactone, drospirenone can help decrease fluid retention. Also, drospirenone has antiandrogenic activity, which means that it works against testosterone and other "male" hormones. All women have a small amount of these "male" hormones that can cause acne and other problems, and drospirenone may help counteract the effects of testosterone. However, drospirenone may increase the level of potassium in your blood, which can be a problem for some women.
Angeliq is a continuous (not cyclic) hormone replacement therapy (HRT) medication. In other words, it is taken nonstop, without any breaks from either of the hormones.