At this time, both strengths of Activella (estradiol/norethindrone) are available in generic form. Both generic versions have been given an "AB" rating by the FDA, which means they are considered equivalent to the brand-name drug.
Activella® (estradiol/norethindrone) is a hormone replacement therapy medication approved for the following uses:
- Preventing osteoporosis in postmenopausal women
- Treating menopausal symptoms, such as hot flashes and vaginal dryness.
Activella contains an estrogen (estradiol) and a progestin (norethindrone), and is approved only for women who still have a uterus (who have not had a hysterectomy).
Activella is made by Novo Nordisk. However, it has come off patent and is also available as a generic.
Generic Activella is available in the following strengths:
- Estradiol/norethindrone 1 mg/0.5 mg
- Estradiol/norethindrone 0.5mg/0.1 mg.
Generic Activella is made by the following companies:
- Breckenridge Pharmaceuticals
- Teva Pharmaceuticals USA.
Teva has chosen to give their version of generic Activella a different name -- Mimvey™ -- rather than use a standard "generic" name.
All generic medications must undergo certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns each generic a rating. An "AB" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. The generic versions of Activella currently available have an "AB" rating, meaning they should be equivalent to Activella.
However, generic medications are allowed to have different inactive ingredients than the brand-name medication. This might include fillers, dyes, or other ingredients that may cause problems for people with allergies or sensitivities.